Our Products

One box solution for
mass spectrometry detection

Using miniaturised chip-based technology, our patented MiD products and integrated software provide immediate insights into biological or chemical samples and reactions.


Years of experience

The 4500 MiD® combines the vacuum system, electronics and computer inside one box. With no floor pump ever needed, it can be installed where no other mass spectrometer can be easily deployed, all while retaining the performance of a conventional mass spectrometer system.

The addition of the Microsaic MiDas™ compact interface sampling module means the 4500 MiD® can be easily deployed in a large variety of on-line, at-line and off-line applications.

  • Small footprint enables deployment anywhere within laboratory or processing facilities

  • Fully integrated and robust system, with no external vacuum pumps, and no external PC

  • Easy to use, simply ‘plug and play’ consumables

  • Low maintenance costs with completely tool-less front-end

Chip Based Technology

Featuring Microsaic’s three main patented chip-based technologies, the ionchip®, spraychip® and vac-chip™, the 4500 MiD® is reliable, robust, and user-friendly, with increased mass range, a completely tool-less front-end for enhanced control, an intuitive and robust user interface, and improved electronics. A change in front-end alignment has also strengthened system uptime while reducing the deposition of contaminants downstream.


Mass Range

Increasing the mass range to 1400 m/z opens up a new range of applications, including peptide analysis using Nano LC-MS, which is ideal for the 4500 MiD®’s extremely efficient ESI source, and its strong propensity towards multiple charging.

Easy to operate and maintain, the Microsaic 4500 MiD® also offers reduced solvent, nitrogen and power consumption to lower operating costs and provide a greener solution for mass detection.

Technical Spec
Dimensions 55 x 35 x 25 cm (22 x 14 x 10 in.) (including PC, pump and exhaust)
Weight 32 kg (including PC, pump and exhaust)
Ion Source spraychip® – electrospray ionization source
Ionization Modes Positive and negative ESI
Sample Inlet Compatible with standard capillaries and unions e.g., 1/32” tubing
Flow Rate Range 0.3-2000 µL/min
Mass Analyzer ionchip® – quadrupole mass filter
Mass Range 50-1400 m/z
Mass Accuracy ± 0.3 m/z in full scan*
Mass Resolution 0.7 m/z ± 0.1 @ FWHM*
Sensitivity 10pg of reserpine yields a peak in SIM mode with a S/N ratio of 10:1 (RMS)
Interface vac-chip™ – off axis microengineered atmospheric pressure interface
Detector Electron multiplier
Dynamic Range 3-4 orders of magnitude
Scan Modes Full scan, SIM (8m/z channels), simultaneous scan/SIM, and timed SIM
Scan Rate m/z 1,500/s (7,500 pts/s)
Pumping System Integrated oil-free pumps (no floor pump needed)
Software Control Masscape® Clarity, PrepCon, Remote Operations Protocol
Connections Ethernet, 5 x USB
2 x digital in (e.g., LC trigger input), 2 x digital out
4 x in (e.g.; UV Trace), 4 x out (e.g., triggering external device)
1 x RS232 (e.g., syringe pump control)
Utility requirements
Power Requirements Power: 250W (operating), 300 W (peak)
Line voltage: 100-240 V AC±10%
Line frequency: 50/60 Hz
Nitrogen Gas Pressure 2-6 bar (29-87 psi)
Purity (≥99,5%)
6mm OD push fit connection
Pump Exhaust Exhaust connects to an 8 mm OD push fit

Across industries,
across the world

As award-winning pioneers in miniaturised mass spec technology, we offer customised, turnkey solutions to multiple industries across the world.